{"id":48654,"date":"2026-05-15T14:05:07","date_gmt":"2026-05-15T11:05:07","guid":{"rendered":"https:\/\/umfst.ro\/?post_type=centru-ucsdt&#038;p=48654"},"modified":"2026-05-25T14:19:22","modified_gmt":"2026-05-25T11:19:22","slug":"centrul-de-studii-experimentale","status":"publish","type":"centru-ucsdt","link":"https:\/\/umfst.ro\/en\/universitate\/cercetare\/unitatea-de-cercetare-stiintifica-si-dezvoltare-tehnologica\/centrul-de-studii-experimentale\/","title":{"rendered":"Experimental Station"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Medicina Experimental\u0103 a constituit, \u00eenc\u0103 din anii 1960\u20131970, un domeniu de referin\u021b\u0103 \u00een activitatea de cercetare desf\u0103\u0219urat\u0103 \u00een cadrul Universit\u0103\u021bii. \u00cen acea perioad\u0103, preocup\u0103rile cercet\u0103torilor s-au concentrat asupra realiz\u0103rii primelor transplanturi cardiace din \u021bar\u0103, marc\u00e2nd astfel un moment definitoriu pentru cercetarea medical\u0103 rom\u00e2neasc\u0103. Prin urmare, Sta\u021bia Experimental\u0103 \u0219i Biobaza universit\u0103\u021bii de\u021bin o tradi\u021bie \u00eendelungat\u0103 \u0219i valoroas\u0103 \u00een sfera cercet\u0103rii experimentale. <br><br>O etap\u0103 important\u0103 de modernizare a avut loc \u00een anul 2005, c\u00e2nd Sta\u021bia Experimental\u0103 a fost supus\u0103 unui amplu proces de renovare, ce a inclus reamenajarea \u0219i recompartimentarea spa\u021biilor, precum \u0219i \u00eenfiin\u021barea unui laborator de diagnostic radiologic veterinar. <br><br>De-a lungul anilor, \u0219i Biobaza a beneficiat de mai multe interven\u021bii de renovare \u0219i reabilitare, adapt\u00e2ndu-se permanent cerin\u021belor moderne ale cercet\u0103rii biomedicale. \u00cen prezent, aceasta este dotat\u0103 cu dou\u0103 s\u0103li de opera\u021bii, dedicate animalelor de talie mare \u0219i mic\u0103, spa\u021bii destinate testelor comportamentale, precum \u0219i compartimente specializate pentru cre\u0219terea animalelor conven\u021bionale, a celor modificate genetic \u0219i a exemplarelor imunocompromise.<\/p>","protected":false},"excerpt":{"rendered":"<p>Medicina Experimental\u0103 a constituit, \u00eenc\u0103 din anii 1960\u20131970, un domeniu de referin\u021b\u0103 \u00een activitatea de cercetare desf\u0103\u0219urat\u0103 \u00een cadrul Universit\u0103\u021bii. \u00cen acea perioad\u0103, preocup\u0103rile cercet\u0103torilor s-au concentrat asupra realiz\u0103rii primelor transplanturi cardiace din \u021bar\u0103, marc\u00e2nd astfel un moment definitoriu pentru cercetarea medical\u0103 rom\u00e2neasc\u0103. Prin urmare, Sta\u021bia Experimental\u0103 \u0219i Biobaza universit\u0103\u021bii de\u021bin o tradi\u021bie \u00eendelungat\u0103 \u0219i [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":36774,"parent":17078,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"43132,47632,47855,46252,34747,35858","_relevanssi_noindex_reason":"","footnotes":""},"class_list":["post-48654","centru-ucsdt","type-centru-ucsdt","status-publish","format-standard","has-post-thumbnail","hentry"],"meta_box":{"mail":"biobaza@umfst.ro","telefon":"+40-265-215.551, int 143","adresa_centru":"Strada Gh. Marinescu, nr. 38, T\u00e2rgu Mure\u0219, 540142 Rom\u00e2nia","facebook":"","website_centru":"","echipa":"<p>Echipa este format\u0103 din tineri cercet\u0103tori doctoranzi \u0219i postdoctoranzi, profund dedica\u021bi activit\u0103\u021bii \u0219tiin\u021bifice \u0219i pasiona\u021bi de domeniul cercet\u0103rii experimentale. Ace\u0219tia manifest\u0103 o aten\u021bie deosebit\u0103 fa\u021b\u0103 de cre\u0219terea \u0219i bun\u0103starea animalelor de laborator, abord\u00e2nd munca lor cu empatie, responsabilitate \u0219i respect fa\u021b\u0103 de fiecare exemplar. Prin profesionalismul \u0219i implicarea lor, contribuie esen\u021bial la men\u021binerea unor condi\u021bii optime pentru desf\u0103\u0219urarea activit\u0103\u021bilor de cercetare. \u00cen prezent, echipa permanent\u0103 este alc\u0103tuit\u0103 dintr-un coordonator \u0219tiin\u021bific, un coordonator administrativ, doi medici veterinari, un tehnician veterinar \u0219i doi \u00eengrijitori de animale.<\/p>\n","servicii":"<ul>\n<li>Coordonarea \u0219i preg\u0103tirea logisticii, \u00een colaborare cu partenerii de cercetare, necesare pentru desf\u0103\u0219urarea proiectelor din domeniul medicinei experimentale.<\/li>\n<li>Organizarea, preg\u0103tirea \u0219i realizarea componentelor experimentale ale diverselor proiecte de cercetare, lucr\u0103ri de diplom\u0103, teze de doctorat \u0219i postdoctorat, \u00een concordan\u021b\u0103 cu limitele de competen\u021b\u0103 profesional\u0103, al\u0103turi de cercet\u0103tori, cadre didactice, medici, doctoranzi, postdoctoranzi \u0219i studen\u021bi.<\/li>\n<li>Preg\u0103tirea animalelor de laborator \u00een vederea efectu\u0103rii interven\u021biilor solicitate de cadre didactice \u0219i studen\u021bi, \u00een cadrul activit\u0103\u021bilor practice sau experimentale.<\/li>\n<li>Asigurarea asisten\u021bei medico-veterinare pe durata interven\u021biilor chirurgicale \u0219i a experimentelor realizate pe animale de laborator.<\/li>\n<li>Efectuarea interven\u021biilor chirurgicale experimentale pe animale de laborator, la solicitarea cadrelor didactice sau \u00een contextul proiectelor de cercetare.<\/li>\n<li>Participarea la analiza \u0219i interpretarea rezultatelor experimentale, \u00een raport cu competen\u021bele profesionale ale personalului implicat.<\/li>\n<li>Oferirea de asisten\u021b\u0103 \u0219i monitorizare postoperatorie pentru animalele supuse interven\u021biilor experimentale.<\/li>\n<li>Manipularea, prelucrarea \u0219i gestionarea materialelor biologice prelevate de la animalele de laborator, cu respectarea normelor etice \u0219i de siguran\u021b\u0103 biologic\u0103.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong><em>Aparatur\u0103:<\/em><\/strong><\/p>\n<p><strong><em>Bloc Operator Animale Mari<\/em><\/strong><\/p>\n<p><em>Pompa de circula\u021bie extracorporial\u0103 (Sorin Group 2017)<\/em><\/p>\n<p><em>Analizor de gaze \u0219i electroli\u021bi (ASTRUP -ABL90 \u2013 Radiometer)<\/em><\/p>\n<p><em>Automated Coagulation Timer (Medtronic ACT Plus)<\/em><\/p>\n<p><em>Aspirator chirurgical (CaMi Hospivac 400)<\/em><\/p>\n<p><em>Electrocauter (Surtron Flash 200)<\/em><\/p>\n<p><em>Sistem Burghiu Neurochirurgie \u2013 (Elan4electro \u2013 GA800 -Aesculap)<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong><em>Bloc Operator Animale Mici<\/em><\/strong><\/p>\n<p><em>Small animal inhalatory anesthesia Machine (R550IE \u2013 RWD)<\/em><\/p>\n<p><em>Small animal ventilator (Ventstar R415 \u2013 RWD)<\/em><\/p>\n<p><em>Veterinary Oxygen Concentrator (ROC-5A, RWD)<\/em><\/p>\n<p><em>Robot Stereotaxic (SD604 - Neurostar)<\/em><\/p>\n<p><em>Pomp\u0103 Injectomat (Perfusor Space, Braun)<\/em><\/p>\n<p><em>Pomp\u0103 Peristaltic\u0103 (FlexiPump, Interscience)<\/em><\/p>\n<p><em>Veterinary Chemistry Analyzer (Element RC, Scil+)<\/em><\/p>\n<p><em>AutoHematology Analyzer (BC-60R, Mindray)<\/em><\/p>\n<p><em>Centrifug\u0103 4000rpm (XC-2415)<\/em><\/p>\n<p><em>Micro-centricug\u0103 6000rpm (VetFuge - Scil)<\/em><\/p>\n<p><em>Incubator (Cultura M \u2013 70700, Almedica AG)<\/em><\/p>\n<p><em>Baie ultrasonic\u0103 \u2013 (D-78224, Elma)<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong><em>Sistem de cu\u0219ti ventilate individual (IVC) - pentru men\u021binerea coloniilor de \u0219oareci transgenici \u0219i imunocompromi\u0219i<\/em><\/strong><\/p>\n<p><em>3 Racks \u2013 cu 63, 54 \u0219i 72 de cu\u0219ti \u0219i 2 unit\u0103\u021bi de ventilare (Tecniplast, Italy)<\/em><\/p>\n<p><em>Hot\u0103 cu flux laminar pentru schimbarea\/cur\u0103\u021barea cu\u0219tilor (9CS481TNNN, Tecniplast)<\/em><\/p>\n<p><em>Sterilizator cu abur (SOL6613K, Getinge)<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong><em>Laboratorul de Studii Comportamentale<\/em><\/strong><\/p>\n<p><em>Water Maze (LE82090, Panlab Harvard)<\/em><\/p>\n<p><em>Barnes Maze ( AnyMaze)<\/em><\/p>\n<p><em>Y-Maze (Panlab, Harvard)<\/em><\/p>\n<p><em>Hot Plate (LE7406, Panlab Harvard)<\/em><\/p>\n<p><em>Sistem de telemetrie implantabil (EasyTel, Emka)<\/em><\/p>\n<p><em>Data Logger (LE8825, Panlab Harvard)<\/em><\/p>\n<p><em>Software Video Traking Smart 3.0<\/em><\/p>\n<p><em>Behavioral Traking Software (AnyMaze) <\/em><\/p>\n<p><em>In-depth analysis ecgAUTO v3.3 (Emka)<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong><em>Laboratorul de Imagistic<\/em><\/strong><strong><em>\u0103<\/em><\/strong><\/p>\n<p><em>Micro-CT (SkyScan1276 Bruker)<\/em><\/p>\n<p><em>C-Arm (Zenition70-Philips)<\/em><\/p>\n<p><em>Sistem de Radiologie full digital (VXR-DR - DRGEM, Korea)<\/em><\/p>\n<p><em>Sistem scanere 3D Tumori (Peirra TM900)<\/em><\/p>\n<p><em>Microscop Binocular cu camer\u0103 video (Nikon\/KoPa)<\/em><\/p>\n<p><em>Diagnostic Ultrasound System (DC-7, Mindray)<\/em><\/p>\n","activitati_de_cercetare":"<ul>\n<li>Derularea de proiecte de cercetare preclinic\u0103 \u00een domeniul medicinei experimentale, cu utilizarea modelelor animale mici \u0219i mari.<\/li>\n<li>Dezvoltarea \u0219i validarea de modele experimentale de boal\u0103 (cardiovasculare, neurologice, oncologice etc.), \u00een vederea test\u0103rii de noi proceduri diagnostice \u0219i terapeutice.<\/li>\n<li>Realizarea de interven\u021bii chirurgicale experimentale avansate, inclusiv proceduri cu circula\u021bie extracorporeal\u0103 \u0219i monitorizare complex\u0103 perioperatorie.<\/li>\n<li>Evaluarea func\u021bional\u0103 \u0219i comportamental\u0103 a animalelor de laborator prin teste standardizate \u0219i sisteme moderne de analiz\u0103 video-computerizat\u0103.<\/li>\n<li>Utilizarea tehnicilor de imagistic\u0103 avansat\u0103 (micro-CT, radiologie digital\u0103, ecografie, C-arm) pentru monitorizarea evolu\u021biei modelelor experimentale \u0219i cuantificarea rezultatelor.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Proiecte de cercetare<\/strong><\/p>\n<ul>\n<li>Evaluarea poten\u021bialului antioxidant al carvediolului comparativ cu vit.E \u00een cazul unui tratament cu zidovudin\u0103 (studiu suspendat)<\/li>\n<li>Canabidiolul ca adjuvant \u00een terapia antiepileptic\u0103 \u2013 interac\u021biunile \u0219i efectele combina\u021biei canabidiol \u2013 levetiracetam (studiu finalizat)<\/li>\n<li>Evaluarea riscului teratogen, toxic fetal \u0219i tardiv al benzidaminei \u2013 studiu pe animal (studiu finalizat)<\/li>\n<li>Evaluarea formul\u0103rii polifenolilor din Laurus nobilis \u00een nanoparticule asupra biodisponibilit\u0103\u021bii \u0219i toxicit\u0103\u021bii (studiu \u00een curs)<\/li>\n<li>Studiu non-clinic referitor la evaluarea interac\u021biunilor medicamentoase la nivelul izoenzimei CYP1A2 a aripripazolului cu inhibitori \u0219i inductori enzimatici (studiu \u00een curs)<\/li>\n<li>Photochemical crosslinking of tarsal collagen as a treatment for eyelid laxity: Mechanical biaxial evaluation of strengthening and stiffening induced in ex-vivo tarsal tissue (studiu \u00een curs)<\/li>\n<li>Celulele intramurale ca biomarkeri \u0219i \u021binte terapeutice pentru boala Alzheimer (studiu \u00een curs)<\/li>\n<li>Role of HIV-1 matrix protein p17 variants in lymphomagenesis: development of new diagnostic tools and therapeutics approaches (studiu \u00een curs)<\/li>\n<li>Studiul efectului canabidiolului asupra depresiei \u0219i consumului de alcool (studiu \u00een curs)<\/li>\n<li>\u021aintirea unei noi c\u0103i fibrotice pentru a \u00eembun\u0103t\u0103\u021bi predic\u021bia \u0219i tratamentul \u00een insuficien\u021ba cardiac\u0103 \u2013 Target-HF (studiu \u00een curs)<\/li>\n<li>Regenerarea tubului digestiv dup\u0103 utilizarea unei matrice extracelulare (studiu \u00een curs)<\/li>\n<li>Efectele vasodilatatoare \u0219i a senescen\u021bei asupra \u00eemb\u0103tr\u00e2nirii \u2013 pe model murin (studiu \u00een curs)<\/li>\n<li>Ac\u021biunea canabidiolului \u00een modelul de depresie indus\u0103 prin bulbectomie olfactiv\u0103 la \u0219obolani (studiu \u00een curs)<\/li>\n<li>Studiul administr\u0103rii cronice a streptozotocinei asupra func\u021biilor cognitive la modelul experimental al bolii Alzheimer (studiu \u00een curs)<\/li>\n<li>Evaluarea in vivo a biocompatibilit\u0103\u021bii scafoldurilor din colagen stabilizat pentru ingineria \u021besutului valvular cardiac (studiu \u00een curs)<\/li>\n<li>Rolul proteinei matriceale p17 a HIV-1 \u00een patogeneza tulbur\u0103rilor neurocognitive (studiu \u00een curs)<\/li>\n<li>Managementul pre- \u0219i postnatal al herniei diafragmatice congenitale (studiu \u00een curs)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","publicatii_centru":"","patente_brevete_de_inventie":""},"_links":{"self":[{"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/centru-ucsdt\/48654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/centru-ucsdt"}],"about":[{"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/types\/centru-ucsdt"}],"author":[{"embeddable":true,"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/comments?post=48654"}],"version-history":[{"count":0,"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/centru-ucsdt\/48654\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/pages\/17078"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/media\/36774"}],"wp:attachment":[{"href":"https:\/\/umfst.ro\/en\/wp-json\/wp\/v2\/media?parent=48654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}