{"id":49559,"date":"2026-06-11T13:55:34","date_gmt":"2026-06-11T10:55:34","guid":{"rendered":"https:\/\/umfst.ro\/"},"modified":"2026-06-11T13:55:35","modified_gmt":"2026-06-11T10:55:35","slug":"laboratorul-de-studii-preclinice","status":"publish","type":"centru-ucsdt","link":"https:\/\/umfst.ro\/fr\/universitate\/cercetare\/unitatea-de-cercetare-stiintifica-si-dezvoltare-tehnologica\/laboratorul-de-studii-preclinice\/","title":{"rendered":"Laboratorul de Studii Preclinice"},"content":{"rendered":"<p>Echipa noastr\u0103, format\u0103 din speciali\u0219ti \u0219i reziden\u021bi \u00een farmacologie clinic\u0103, investigheaz\u0103 modul \u00een care re\u021belele complexe de interac\u021biuni influen\u021beaz\u0103 ac\u021biunea medicamentelor, cu un accent particular pe reac\u021biile adverse cutanate \u0219i pe determinan\u021bii regimurilor terapeutice care modeleaz\u0103 performan\u021ba clinic\u0103. Prin integrarea farmacologiei sistemice cu cercetarea transla\u021bional\u0103, urm\u0103rim rafinarea strategiilor de dozare \u0219i reducerea riscurilor evitabile.<\/p>","protected":false},"excerpt":{"rendered":"<p>Echipa noastr\u0103, format\u0103 din speciali\u0219ti \u0219i reziden\u021bi \u00een farmacologie clinic\u0103, investigheaz\u0103 modul \u00een care re\u021belele complexe de interac\u021biuni influen\u021beaz\u0103 ac\u021biunea medicamentelor, cu un accent particular pe reac\u021biile adverse cutanate \u0219i pe determinan\u021bii regimurilor terapeutice care modeleaz\u0103 performan\u021ba clinic\u0103. Prin integrarea farmacologiei sistemice cu cercetarea transla\u021bional\u0103, urm\u0103rim rafinarea strategiilor de dozare \u0219i reducerea riscurilor evitabile.<\/p>","protected":false},"author":25,"featured_media":43061,"parent":17078,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"45657,23228,42563,43204,37231,20259","_relevanssi_noindex_reason":"","footnotes":""},"class_list":["post-49559","centru-ucsdt","type-centru-ucsdt","status-publish","format-standard","has-post-thumbnail","hentry"],"meta_box":{"mail":"erika.ban@umfst.ro","telefon":"","adresa_centru":"","facebook":"","website_centru":"","echipa":"<p>Lector univ. Dr. Erika-Gy\u00f6ngyi B\u00e1n PhD \u2013 Medic primar farmacologie clinica<\/p>\n<p>Asist. Univ dr. Eszter-Anna Dho-Nagy drd \u2013 Medic specialist farmacologie clinica<\/p>\n<p>Asist. Univ dr. Hanna Sebesi drd \u2013 Medic rezident farmacologie clinica<\/p>\n","servicii":"<p>Analiza interac\u021biunilor medicamentoase utiliz\u00e2nd diverse abord\u0103ri de modelare<\/p>\n<p>Caracterizarea reac\u021biilor adverse cutanate, incluz\u00e2nd examin\u0103ri ultrasonografice \u0219i evaluarea mecanismelor implicate<\/p>\n<p>Optimizarea regimurilor terapeutice prin evaluare farmacocinetic\u0103\/farmacodinamic\u0103 \u0219i rafinarea dozelor pe baze evidence\u2011based<\/p>\n<p>Evaluarea siguran\u021bei \u0219i variabilit\u0103\u021bii pentru combina\u021bii medicamentoase noi sau complexe<\/p>\n<p>Suport consultativ pentru studii de farmacologie clinic\u0103 \u0219i proiecte de cercetare transla\u021bional\u0103<\/p>\n","activitati_de_cercetare":"<p>Laboratorul nostru desf\u0103\u0219oar\u0103 cercet\u0103ri focalizate asupra mecanismelor care stau la baza interac\u021biunilor medicamentoase, a determinantilor moleculari \u0219i imunologici ai reac\u021biilor adverse cutanate \u0219i a optimiz\u0103rii cantitative a regimurilor terapeutice. Prin integrarea experimentelor mecanistice, a evalu\u0103rilor de siguran\u021b\u0103 bazate pe biomarkeri \u0219i a model\u0103rii PK\/PD, gener\u0103m dovezi care sus\u021bin o farmacoterapie mai sigur\u0103, mai precis\u0103 \u0219i cu aplicabilitate clinic\u0103 direct\u0103.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Proiecte de cercetare<\/strong><\/p>\n<ul>\n<li>Evaluarea pielii utiliz\u00e2nd Dermus SkinScanner\u2011U<\/li>\n<li>Managementul durerii \u2013 o provocare pentru farmacologul clinician<\/li>\n<li>Interac\u021biuni medicamentoase \u00een bolile autoimmune<\/li>\n<\/ul>\n","publicatii_centru":"<ul>\n<li>COVID-19 and antipsychotic therapy: unraveling the thrombosis risk, EA Dho-Nagy, A Brassai, P Lechsner, C Ureche et al - International Journal of Molecular Sciences, 2024<\/li>\n<li>Novel Strategy in the Detection of Adverse Cutaneous Drug Reactions: A Case Series Study, EG B\u00e1n, P Lechsner, EA Dho-Nagy, MA Balan et al - Diagnostics, 2024<\/li>\n<li>Intersecting Pathways: Amphetamines and Opioids in the Landscape of Chronic Pain Therapy, EG Ban, P Lechsner, EA Dho-Nagy, MA An, T Strob - NAUNYN-SCHMIEDEBERGS ARCHIVES OF Pharmacology, 2024<\/li>\n<\/ul>\n","patente_brevete_de_inventie":""},"_links":{"self":[{"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/centru-ucsdt\/49559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/centru-ucsdt"}],"about":[{"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/types\/centru-ucsdt"}],"author":[{"embeddable":true,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/comments?post=49559"}],"version-history":[{"count":1,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/centru-ucsdt\/49559\/revisions"}],"predecessor-version":[{"id":49560,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/centru-ucsdt\/49559\/revisions\/49560"}],"up":[{"embeddable":true,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/pages\/17078"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/media\/43061"}],"wp:attachment":[{"href":"https:\/\/umfst.ro\/fr\/wp-json\/wp\/v2\/media?parent=49559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}