{"id":19843,"date":"2023-12-07T13:22:35","date_gmt":"2023-12-07T11:22:35","guid":{"rendered":"https:\/\/umfst.ro\/?page_id=19843"},"modified":"2024-05-14T11:59:12","modified_gmt":"2024-05-14T08:59:12","slug":"rolul-axei-microbiota-creier-in-progresia-sclerozei-laterale-amiotrofice","status":"publish","type":"page","link":"https:\/\/umfst.ro\/hu\/universitate\/departament-proiecte-europene\/anunturi\/cercetare\/fonduri-nationale\/uefiscdi\/rolul-axei-microbiota-creier-in-progresia-sclerozei-laterale-amiotrofice\/","title":{"rendered":"ROLUL AXEI MICROBIOTA-CREIER IN PROGRESIA SCLEROZEI LATERALE AMIOTROFICE"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"19843\" class=\"elementor elementor-19843\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-13a0d9f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"13a0d9f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-22b8ab5\" data-id=\"22b8ab5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5ddbea5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5ddbea5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a459a1d\" data-id=\"a459a1d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0208168 elementor-widget elementor-widget-text-editor\" data-id=\"0208168\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2>ROLUL AXEI MICROBIOTA-CREIER IN PROGRESIA SCLEROZEI LATERALE AMIOTROFICE PN-III-P1-1.1-TE-2021-0960<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f169c34 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f169c34\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a925d63\" data-id=\"a925d63\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-083c6e3 elementor-widget elementor-widget-text-editor\" data-id=\"083c6e3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div id=\"c11074\" class=\"frame frame-default frame-type-textpic frame-layout-0\"><div class=\"ce-textpic ce-center ce-below\"><div class=\"ce-bodytext\"><p><strong>Obiectivele proiectului<\/strong><\/p><p>Alterarea in productia de acizi grasi cu lant scurt si de hormoni intestinali este asociata cu disbioza microbiotei intestinale si cu inflamatia la pacientii cu scleroza laterala amiotrofica (SLA).<br \/>Dieta influenteaza compozitia microbiotei intestinale si influenteaza cursul progresiv al bolii.<br \/><br \/><strong>Obiectiv principal:<\/strong>\u00a0Evaluarea corelatiei dintre microbiota intestinala si progresia SLA in diferitele fenotipuri progresive folosind profilul SCFAGGYC-PROF.<br \/><br \/><strong>Obiective specifice:<\/strong><\/p><p>1. Identificarea profilului SCFAGGYC-PROF la pacientii cu SLA comparativ cu pacientii sanatosi<\/p><p>2. Identificarea profilului specific microbiotei intestinale pentru pacientii cu SLA<\/p><p>3. Evaluarea evolutiei dinamice a profilului SCFAGGYC-PROF si a profilului genomic al microbiotei la pacientii cu boala rapid progresiva comparativ cu cei cu progresie normala (indentificarea de biomarkeri predictivi ai progresiei SLA)<\/p><p>4. Identificarea impactului pe care il are interventia dietei in progresia bolii si asupra modificarilor microbiotei intestinale in populatia SLA studiata<\/p><p>\u00a0<\/p><p><strong>Design-ului studiului<\/strong><\/p><\/div><div class=\"ce-gallery\" data-ce-columns=\"1\" data-ce-images=\"1\"><div class=\"ce-outer\"><div class=\"ce-inner\"><div class=\"ce-row\"><div class=\"ce-column\"><figure class=\"image\"><a href=\"https:\/\/arhiva.umfst.ro\/fileadmin\/cercetare\/2022\/img\/design_studiu_Motataianu_Anca.png\" rel=\"lightbox[grup11074]\" data-title=\"\"> <img fetchpriority=\"high\" decoding=\"async\" class=\"image-embed-item\" src=\"https:\/\/arhiva.umfst.ro\/fileadmin\/cercetare\/2022\/img\/design_studiu_Motataianu_Anca.png\" alt=\"\" width=\"624\" height=\"480\" \/> <\/a><\/figure><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"c11075\" class=\"frame frame-default frame-type-textpic frame-layout-0\"><div class=\"ce-textpic ce-center ce-below\"><div class=\"ce-bodytext\"><p><strong>Finantat<\/strong><\/p><p>\u00a0<\/p><\/div><div class=\"ce-gallery\" data-ce-columns=\"2\" data-ce-images=\"2\"><div class=\"ce-outer\"><div class=\"ce-inner\"><div class=\"ce-row\"><div class=\"ce-column\"><figure class=\"image\"><img decoding=\"async\" class=\"image-embed-item\" src=\"https:\/\/arhiva.umfst.ro\/fileadmin\/_processed_\/6\/4\/csm_uefiscadi_41bea3fe42.png\" alt=\"\" width=\"200\" height=\"84\" \/><\/figure><\/div><div class=\"ce-column\"><figure class=\"image\"><img decoding=\"async\" class=\"image-embed-item\" src=\"https:\/\/arhiva.umfst.ro\/fileadmin\/_processed_\/a\/7\/csm_ME_688c1b30c1.png\" alt=\"\" width=\"200\" height=\"57\" \/><\/figure><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div id=\"c11076\" class=\"frame frame-default frame-type-textpic frame-layout-0\"><div class=\"ce-textpic ce-center ce-above\"><div class=\"ce-bodytext\"><p>Acest proiect este finantat de catre Ministerul Cercetarii, Inovatiei si Digitalizarii prin cadrul Unitatii Executive pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii \u0219i Inovarii (UEFISCDI).<br \/><br \/><strong>Numar de proiect:<\/strong> PN-III-P1-1.1-TE-2021-0960.<\/p><p>\u00a0<\/p><p><strong>Echipa<\/strong><\/p><p>\u00a0<\/p><table class=\"contenttable\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\"><tbody><tr><td><p>Nume<\/p><\/td><td><p>Rolul<\/p><\/td><\/tr><tr><td><p>Conf. Dr. Motataianu Anca<\/p><\/td><td><p>Director de proiect<\/p><\/td><\/tr><tr><td><p>Dr. Andone Sebastian<\/p><\/td><td><p>Student doctorand<\/p><\/td><\/tr><tr><td><p>Dr. Serban Georgia<\/p><\/td><td><p>Student doctorand<\/p><\/td><\/tr><tr><td><p>Dr. Barcutean Laura<\/p><\/td><td><p>Cercetator postdoctoral<\/p><\/td><\/tr><tr><td><p>Dr. Ion Valentin<\/p><\/td><td><p>Cercetator postdoctoral<\/p><\/td><\/tr><tr><td><p>Dr. Manescu Bogdan<\/p><\/td><td><p>Student doctorand<\/p><\/td><\/tr><tr><td><p>Dr. Crisan Adriana Stela<\/p><\/td><td><p>Student doctorand<\/p><\/td><\/tr><\/tbody><\/table><p><strong>Date contact<br \/><\/strong><strong>Persoana contact:<\/strong> Conf. Dr. Motataianu Anca<br \/><strong>E-mail:<\/strong> <a>anca.motataianu@umfst.ro<\/a><\/p><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4be1411 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4be1411\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d14845c\" data-id=\"d14845c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ae58ade elementor-widget elementor-widget-text-editor\" data-id=\"ae58ade\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span lang=\"FR\" style=\"font-family: 'Times New Roman',serif\"><a href=\"https:\/\/umfst.ro\/fileadmin\/cercetare\/rapoarte-proiecte\/2024_RAPORT_STIINTIFIC_TE74.pdf\">Raport stiintific 2024<\/a>\u00a0<\/span><\/p><p><span lang=\"FR\"><a href=\"https:\/\/umfst.ro\/fileadmin\/cercetare\/rapoarte-proiecte\/2023_RAPORT_STIINTIFIC_TE74.pdf\">Raport stiintific 2023<\/a>\u00a0<\/span><\/p><p><span lang=\"FR\"> <a href=\"https:\/\/umfst.ro\/fileadmin\/cercetare\/rapoarte-proiecte\/2022_RAPORT_STIINTIFIC_TE74.pdf\">Raport stiintific 2022<\/a><\/span><span lang=\"FR\" style=\"font-family: 'Times New Roman',serif\"> <br \/><\/span><\/p><p><span lang=\"FR\" style=\"font-family: 'Times New Roman',serif\">\u00a0<\/span><\/p><p><em>\u00a0<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>ROLUL AXEI MICROBIOTA-CREIER IN PROGRESIA SCLEROZEI LATERALE AMIOTROFICE PN-III-P1-1.1-TE-2021-0960 Obiectivele proiectului Alterarea in productia de acizi grasi cu lant scurt si de hormoni intestinali este asociata cu disbioza microbiotei intestinale si cu inflamatia la pacientii cu scleroza laterala amiotrofica (SLA).Dieta influenteaza compozitia microbiotei intestinale si influenteaza cursul progresiv al bolii. Obiectiv principal:\u00a0Evaluarea corelatiei dintre microbiota [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"parent":17406,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"2391,13292,17398,6273,2383,12070","_relevanssi_noindex_reason":"","footnotes":""},"categories":[145,16],"tags":[],"class_list":["post-19843","page","type-page","status-publish","hentry","category-pagina-cercetare","category-pagina-sidebar"],"meta_box":[],"_links":{"self":[{"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/pages\/19843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/users\/25"}],"replies":[{"embeddable":true,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/comments?post=19843"}],"version-history":[{"count":31,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/pages\/19843\/revisions"}],"predecessor-version":[{"id":25318,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/pages\/19843\/revisions\/25318"}],"up":[{"embeddable":true,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/pages\/17406"}],"wp:attachment":[{"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/media?parent=19843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/categories?post=19843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/umfst.ro\/hu\/wp-json\/wp\/v2\/tags?post=19843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}